Get To Revenue helped Manifold.ai, an AI-powered clinical research platform, modernize their outbound efforts and reduce manual sales workload using a data-driven, automated stack for scalable, personalized prospecting ahead of their Series A funding round.
Manifold.ai is an AI-powered clinical research platform specializing in streamlining and modernizing data and study management for life sciences and healthcare research organizations.
Challenges: Manifold aimed to speed up partnership and client acquisition ahead of its Series A by targeting biotech, biopharma, CRO, and molecular diagnostics companies with its flagship AI platform. The leadership wanted to modernize outbound efforts and reduce manual sales workload using a data-driven, automated stack for scalable, personalized prospecting.
In just 16 weeks, Get To Revenue executed a comprehensive ABM strategy for Manifold built around Clay, HubSpot, and Reply.io.
Weeks 1-4 focused on sourcing, ICP mapping, and messaging foundation – building and personalizing the first 200 leads in Clay for all target segments while setting up lead scoring systems in HubSpot.
Weeks 5-9 saw the rollout of outreach automation, continuing LinkedIn connection growth to 20/day, launching Reply.io campaigns, and integrating systems to automatically sync lead engagement and update lifecycle stages in HubSpot CRM.
Weeks 10-13 activated campaign segmentation with Solution vs Webinar campaigns, launched LinkedIn/Facebook video ads, implemented retargeting across all platforms, and established automated lifecycle progression from Lead to MQL/SQL/Engaged/Opportunity.
Weeks 14-16 optimized performance, switched RLSA to direct targeting, and implemented sales handoff automation with instant rep alerts and SDR/AE assignment for meeting bookers and webinar SQLs.
With 3,000 primary buyers across 1,800 companies contacted and achieving industry-beating conversion rates, Manifold is now positioned for accelerated growth with a scalable, automated outbound system.
3,000
1,200+
21
5
$1.2 million
We suggested to launch and automate outbound outreach for Manifold, using Clay, HubSpot, and Reply.io. The focus: build a scalable program targeting Life Science companies such as Biotech, Biopharma, CRO, Molecular Diagnostics Centers to grow the pipeline and book meetings with high-fit accounts.
Get To Revenue recommended the ABM Package, which included setting up the tech stack for their ABM campaign with Clay, Reply and Hubspot, but also included paid ads on LinkedIn, Google Search Ads (RLSA) and Meta Ads.
Automation Tech Stack
Target Audience
Biotech, biopharma, CRO, diagnostics, and molecular population database centers.
Channels
Goals
Clay Lead Sourcing: Targeted lead research and enrichment for biotech, biopharma, CRO, and molecular diagnostics companies with AI-powered ICP mapping, company classification, and personalized messaging generation.
Reply.io Sequencing: Automated email outreach with Solution Campaign sequences (demo booking) and Webinar Campaign sequences (event registration), integrated with LinkedIn connection requests and automated positive reply detection.
HubSpot Automation: CRM management with predictive lead scoring, automated lifecycle progression, nurturing workflows, and sales handoff automation with instant rep alerts and SDR/AE assignment.
Processing large volumes of records with AI—such as classifying ICPs, analyzing funding/revenue, identifying core offerings, or sourcing news for messaging—is costly. We typically ask clients to sign up for their own API keys with OpenAI (ChatGPT) and Gemini (Flash), since this is more affordable than relying solely on Clay’s built-in AI integration.
For high-reasoning tasks (business model analysis, ICP segmentation), we use advanced models like Claude or GPT-5—and minimize usage with multi-step prompting. For example, we use a cheaper model first for keyword detection, then escalate to a more expensive model for deeper analysis only on low-confidence records.
Clay often includes records for companies with high default rates or recent acquisitions. We must verify that each company is still active, frequently by checking the HTTP status of its website before outreach.
Connection and reply rates improved significantly when one of the founders personally participated in Reply.io outreach. Active leadership involvement increased top-of-funnel success and accelerated down-funnel conversions.
